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Strong correlations were also noted for taurochenodeoxycholic acid (TDCA) and glycochenodeoxycholic acid (GCDC)

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Cost and Manufacturing Complexity The manufacturing costs of peptide drugs are generally higher than small molecule medications due to more complex synthesis or production processes

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We selected the joint pathway analysis module from the MetaboAnalyst platform ( which aims to represent whether the HPL-induced proteins and metabolites in a particular pathway are significantly enriched ( p values (unweighted) were chosen to evaluate the role of selected proteins or metabolites