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Mechanism-based inhibition of human persulfide dioxygenase by -glutamyl-homocysteinyl-glycine

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An algorithm originally written to model sites of Cytochrome P450 metabolism (called XenoSite) finds clear patterns in molecular structure that identify sites of reactivity within reactive molecules with 90.8% accuracy and separate reactive and unreactive molecules with 80.6% accuracy

Physiol Res

This report aims to explore the genetic predispositions that impact liver and gallbladder health, including conditions such as fatty liver, hepatitis C, and gallstones

GSTZ1-1 is a bifunctional enzyme that, acting as maleylacetoacetate isomerase, is also involved in the metabolic degradation of phenylalanine and tyrosine 83