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GST loses its ability to bind Glutathione-Superflow Resin when denatured, and consequently strong denaturants such as guanidine-HCl or urea must not be used in the purification buffers

Newberg, N-Acetyl Cysteine Administration Is Associated with Increased Cerebral Glucose Metabolism In Patients With Multiple Sclerosis, Frontiers in Neurology , DOI: 10.3389/fneur.2020.00088, 2020

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