Its chemical stability and rapid intestinal absorption overcome the inherent limitation of free butyrate, including short plasma half-life and failure to achieve therapeutic concentrations in target tissues
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10.1007/s00384-005-0773-y Lee KB, Pi KB, Kim EB, Rho BS, Kang SK, Lee HG, Choi YJ: Glutathione-mediated response to acid stress in the probiotic bacterium, Lactobacillus salivarius
This modification directly modulates transcriptional activity and gene expression, thereby establishing a mechanistic link between cellular metabolism and transcriptional regulation (107,108)
The precipitate is then suspended in water, wherein the glutathione can be released by reaction with hydrogen sulfide or the salts thereof (CN106220708) or by an electrochemical process (EP2439312, WO2014/133129)