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Its selective signaling profile makes it a valuable tool for researchers studying targeted metabolic pathways, adipose dynamics, and peptide-driven energy regulation

It is important to note that all current evidence derives from in vitro cellular models and in vivo animal studies, and no human clinical trials have been conducted as of February 2026

Because the pancreas provides critical enzymes, as well as calcium required for vitamin B 12 absorption, pancreatic insufficiency may contribute to vitamin B 12 deficiency