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Melasma can be resistant to treatment and usually requires combination therapy and multiple therapeutic approaches, of which hydroquinone is one component
Samiec PS, Drews-Botsch C, Flagg EW, Kurtz JC, Sternberg P, Reed RL, Jones DP: Glutathione in human plasma: decline in association with aging, age-related macular degeneration, and diabetes
Unfortunately, overproduction of ROS in DS is not normally compensated by antioxidant mechanisms (Schuchmann and Heinemann, 2000)
Within its role as the bodys most important antioxidant, Glutathione is capable of preventing damage to important cellular components caused by reactive oxygen species (such as free radicals, peroxides, lipid peroxides), xenobiotics, and heavy metals Glutathione also plays important roles in nutrient metabolism, and regulation of cellular events including
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