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Current literature emphasizes mechanistic exploration rather than definitive biological outcomes
& Aaseth, J
The most relevant neuropathological feature of SCA3 is the presence of intraneuronal inclusions of mutant ATXN3 proteins in postmortem patient brains, as a consequence of the change in conformation of ATXN3 due to the expanded polyQ tract
Collagen Production: Enhances collagen production, leading to smoother, more youthful skin
Due to shunting inhibition, this value is more depolarized (-55 mV) than the mean value or resting value of membrane potential 154