The compound is still working through Eli Lilly's TRIUMPH Phase 3 program, with seven additional trial readouts expected through 2026 alongside the already-reported TRIUMPH-4 data from December 2025
The directional migration is mediated by secreted chemokines that form a concentration gradient towards the site of inflammation (Koopmann and Krangel, 1997)
DSIP (Delta Sleep Inducing Peptide), also called Emideltide, is a nonapeptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (CAS 62568-57-4, PM 848.82 Da)
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Chronic conditions with poor blood supply -- where the tissue needs ongoing support to rebuild vasculature -- fit this profile well
They were kept in plastic cages under the environmental conditions were kept at 23 C, 14-hr light and 10-hr dark cycles