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E3 ubiquitin ligases such as Hrd1 play a central role in targeting misfolded ER proteins for degradation

Statements Author contributions CF: Writing original draft

Documentation: review available COA records and the Quality & Testing page for batch-verification standards

However, these tools remain underutilized, leading to potential inconsistencies in evaluating efficacy and safety outcomes in adolescent populations

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This approach not only uncovers intercellular interactions but also provides detailed insights into the cellular microenvironment, offering a powerful framework for exploring complex biological processes and disease mechanisms [287]