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Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element

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In addition, changes in the catecholamine branch of tyrosine metabolism like increase in VMA and decrease in MHPG, and changes in the end products of purine pathway, such as decreases in XAN and HX, were identified in the MDD patients after drug exposure

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