Ferroptosis and human diseases The accumulation of excess iron serves as the primary catalyst for ferroptosis, thereby increasing the vulnerability of various cell types to this form of cell death [82]
Bhowmick NA, Chytil A, Plieth D, Gorska AE, Dumont N, Shappell S, et al
From KPV, a tripeptide that directly suppresses the NF-kB pathway central to psoriatic inflammation, to GHK-Cu, a copper peptide that modulates cytokine production while simultaneously supporting tissue repair, researchers are identifying mechanisms that address psoriasis at its immunological roots rather than merely suppressing surface symptoms
M.JiangH.CunninghamG
IGF-1Ea (MGF) has been shown to have anti-inflammatory effects, but also prolongs the life of macrophages
The exact cause of neuronal cell death in AD has not been fully established but could involve a number of apoptotic, necrotic, pyroptotic, ferropoptotitic and perhaps cuproptotic cell death (Mangalmurti and Lukens, 2022