Intranasal delivery of DSIP is straightforward

Disclosure of interest: FAM, KG, VR, MK, WNW, KB, PH have nothing to disclose Poster Session I - RISK FACTORS - PRIMARY AND SECONDAR PREVENTION 05.00 - RISK FACTORS AND PREVENTION (PRIMARY AND SECONDARY) - 05.01 - PREVENTION P405 - ESOC25-1791 THE IMPACT OF FRAILTY ON STROKE RISK IN ELDERLY PATIENTS WITH ATRIAL FIBRILLATION Natalie Burgos Bencosme 1 , Sarah Rodrguez Santiago 1 , Lucia Antua Montes 1 , Elena Valle Calongue 1 , German Guzman Gutierrez 2 , Sara Fueyo lvarez 1 , Julieth Caballero Velsquez 1 , Eva Lopez Alvarez 1 , Jos Gutirrez Rodrguez 1 , Monserrat Gonzlez Delgado 3 , Jorge Herrera Parra 1 1 Monte Naranco Hospital, Oviedo, Spain, 2 University of Aberdeen-NHS Grampian, Aberdeen, United Kingdom, 3 Central University Hospital of Asturias, Oviedo, Spain Background and Aims: In the context of an ageing population, understanding how elderly individuals with atrial fibrillation (AF) characteristics influence stroke incidence is crucial
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They are polarized tissues due to the differential expression of ion channels, pumps and transporters in the apical and the basolateral sides: (a) epithelial sodium channels (ENaC), Ca 2+ activated chloride channels and the cystic fibrosis transmembrane conductance regulator (CFTR) are present in the apical plasma membrane and (b) the Na + -K + -ATPase ion pump and the Na + -K + -2Cl cotransporter in the basolateral side
If you are deficient, B12 shots are of enormous help
Some versions may also include vitamin B12 for added energy or other compounds like Semaglutide GLP-1 for enhanced support