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Chem Sci 2025:1 Budzianowska A et al (2025) Antioxidants to defend healthy and youthful skincurrent trends and future directions in cosmetology

Although there are a large number of products that help brighten your skin, it is best to go natural

In addition, Nrf2 can also regulate the expression of downstream enzymes such as GST and GR, further improving the cell's antioxidant defense network and enabling cells to more effectively respond to damage caused by oxidative stress

Thus, cystine and GSH cooperate to suppress lipid ROS and ferroptosis in HepG2 cells

Because cellular iron output is mediated by FPN1 and polycupric ferrous oxide enzymes (such as ceruloplasmin), a decrease in the expression of FPN1 or ceruloplasmin can increase the sensitivity of cells to ferroptosis [29,30,31,32]

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