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Spatial-Proteomics Reveals Phospho-Signaling Dynamics at Subcellular Resolution

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In basal-like TN breast cancer, CCL20 promotes bone metastasis by raising the secretion of MMP-2/9 and increasing the receptor activator of nuclear factors-kappa B (NF-B) ligand/osteoprotegerin ratio in breast cancer and osteoblastic cells (108)