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doi: 10.1038/srep01256

Meanwhile, the upstream regulatory mechanism eliciting an imbalance in OA matrix homeostasis needs further investigation

Antioxidants are the heroes in this scenario because they come along and donate one of their electrons to the free radicals (also called reactive oxygen species) and stabilize them

Adverse events were mild to moderate in severity, most commonly gastrointestinal disturbance (207 adverse events, 37%), with similar rates across treatment groups

By affecting these master regulators, GHK-Cu influences hundreds to thousands of downstream genes simultaneously explaining pleiotropic effects