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Notably, some studies have shown that vitamin K1 (chlorophylquinone) can compensate for the damage to the anti-ferroptosis defense mechanism when GPX4 was inhibited or when used with the DHODH inhibitor BQR, and its anti-ferroptosis efficacy was found to be equivalent to that of ferrostatin-1 (Fer-1) [61]

Zhao LH, Yuan QN, Dai AT, He XH, Chen CW, Zhang C, et al

This approach forces a difficult decision between temporary relief and an invasive, end-stage procedure

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