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Future research can uncover new therapeutic strategies by targeting downstream pathways, and effector molecules

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The higher anti-PD-1/PD-L1 response rates in skin cancer relative to other solid tumor types are probably caused, at least in part, by a greater mutational burden

demonstrated that oxidative modification by ROS formed 8-oxoguanine in miRNAs seed regions, which led to adenine mispairing mutation with mRNA, and promoted cardiac hypertrophy

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