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While measurement of LPS in healthy individuals is difficult due to its low levels and issues with contaminated lab equipment, inhibition of LPS-receptor, the toll-like receptor 4 (TLR4), reduces blood pressure (BP) and inflammatory markers (e.g., IL6, macrophage infiltration to the kidneys) in experimental models of hypertension [17, 18]

In clinical trials, tirzepatide demonstrated average weight loss of up to 22.5% of body weight, exceeding the 15% typically seen with semaglutide at maximum doses

Individuals following a vegan or vegetarian diet are at higher risk of developing vitamin B12 deficiency [7]

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