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A recent review on copper hypersensitivity concluded that copper is a weak sensitizer as compared with other metallic compounds 14

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However, it is important to note that there is limited scientific evidence to support these claims

Calcium dynamics in single spines during coincident pre- and postsynaptic activity depend on relative timing of back-propagating action potentials and subthreshold excitatory postsynaptic potentials

M.HuZ.et al

A simple cold pack on the tender area for a few minutes can help numb it and bring down the swelling