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The absence of human clinical data means every individual is essentially running an n=1 experiment

Several etiological factors are most likely involved in the pathogenesis of the impaired barrier function in chronic liver disease, but the four most important ones are direct toxicity of alcohol, portal hypertension, alterations in the intestinal microbiome and altered bile acid signaling

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Its phase 3 trial showing efficacy there, not where the primary outcome is the improvement of the complication