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This may weaken its regenerative and antioxidant effects, as the modified structure may not mimic the natural peptides efficacy

Data Availability The datasets generated and/or analysed during the current study are available from the corresponding author on reasonable request

Clinical Evidence: The SURPASS and SURMOUNT Programs SURPASS Trials in Type 2 Diabetes The SURPASS clinical trial program evaluated tirzepatides efficacy and safety in patients with type 2 diabetes across various clinical scenarios

Anita Skrtic, [email protected] This article was submitted to Translational Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

TB500 is a synthetic fragment of thymosin beta-4 , and it is a systemically acting regenerative peptide

A score of 3 was considered indicative of good quality