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One of the primary reasons patients may require Vitamin B12 injections is pernicious anemiaa condition where the body cannot absorb enough B12 through the digestive tract

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Coenzyme: Nicotinamide adenine dinucleotide (NAD+) is a coenzyme that is involved in many cellular processes, including metabolism, DNA repair, and cell signaling

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Note that due to the relative small size of the rats, rat fistulas regularly appeared as large and complex, and thereby, in this respect, corresponded to the worst presentation in the patients (Klicek et al., 2008