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capillary voltage, 4500 V

The role of autophagy in epileptogenesis and in epilepsy-induced neuronal alterations

We demonstrated that, at low doses (ng), local (intraplantar) or systemic (intraperitoneal) injections of thymulin resulted in hyperalgesia with an increase in proinflammatory mediators, and that this peptide could act directly on the afferent nerve terminals through prostaglandinE2 (PGE2)dependent mechanisms, thus forming a neuroimmune loop involving capsaicinsensitive primary afferent fibers

McNaughton BL, Morris RG

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Furthermore, this plant has a double mechanism of action (increased GABA and decreased GABA-T)