Their distinct, disease-specific distribution in the brain and associations with SVD MRI markers observed in CADASIL suggest that they are indeed a marker of SVD
OConnor C, White KL, Doncescu N et al (2015) NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor
That is particularly relevant when different compounds occupy adjacent commercial keyword clusters but operate through different receptor or transcriptional pathways

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Retrieved 15 May 2008
When retinol still makes sense This is not a case for abandoning retinol entirely