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The senolytic properties of the compound A-1155463 have been demonstrated both in vitro and in vivo, particularly against non-small cell lung cancer (A549) cells induced into senescence by CCC-021-TPP [107]

Storage Requirements That Preserve Potency Once reconstituted, glutathione must be stored at 28C (refrigerator temperature) and used within 28 days

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Lewerenz and Maher, 2015)

Gene expression analysis showed 127 genes altered in a direction that shifts from tissue destruction patterns toward active repair, with repair genes upregulated and inflammatory genes downregulated simultaneously