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Science 343 , 11371140, (2014)
doi: 10.1021/jf102159j
Its also worth calling out that other conditions can cause similar symptoms: Osteoarthritis
Mandal D, Baudin-Creuza V, Bhattacharyya A, Pathak S, Delaunay J, Kundu M, et al
For established cognitive support, the evidence-based options include aerobic exercise (strong evidence for cognitive benefits, especially executive function and processing speed), sleep optimization (critical for cognitive function), Mediterranean diet (modest evidence for cognitive protection over years), treating sleep apnea (significant cognitive improvements when this condition is addressed), treating depression (major cognitive effects when present), donepezil and other approved Alzheimer drugs (modest evidence-based effects in actual Alzheimer disease), and stimulants (well-established for ADHD)
However, most patients notice relief after just one treatment
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