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In a different solvent, these solvation anomalies tend to persist, thus making p K a values in the two solvents linearly proportional

Form of peptides

At the end of this 7-day labelling period ( t = 0 h), samples were collected to verify complete incorporation of the heavy label into cellular proteins

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While acute iron exposure produced minimal biochemical changes and did not sensitize cells to oxidative or ferroptotic challenges, chronic iron exposure induced ferritin upregulation, mitochondrial superoxide accumulation, suppression of GPX4 expression, elevated lipid peroxidation and loss of cellular glutathione (GSH)

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