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Unfortunately, VEGF can also be detrimental because its overexpression can cause inflammation in the nervous system, which in turn can lead to BBB leakage, promote the production of pro-inflammatory cytokines and the occurrence of neurodegeneration (Claire and Larrive 2017

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Any discussion of pineal-gland lineage, circadian biology, or aging-associated pathways is presented solely as research context and does not imply human-use benefits

In a dissenting comment, Sikiric and colleagues said that BPC-157 had been unjustly accused of potentially harmful effects. They pointed to a list of research findings that, in their view, rule out the possibility that the peptide causes cancer and other potential harms

Conclusion Research on DSIP highlights its potential connections to sleep regulation, stress response, neurotransmission, metabolic activity, and other physiological systems