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Les groupes thiol sont maintenus dans un tat rduit une concentration d'environ 5 mM dans les cellules animales

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Drug-induced liver injury has been reported, so pretreatment evaluation should include checking levels of liver enzymes and bilirubin in addition to the usual laboratory testing performed before administration of biologicals

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The narrative format was selected to accommodate heterogeneous evidence spanning preclinical mechanisms, clinical trials, and translational barriers where systematic synthesis would be inappropriate