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Jamei M, Dickinson GL, Rostami-Hodjegan A (2009) A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and genetics: a tale of `Bottom-Up vs`Top-Down recognition of covariates

More information, the D2R antibody from Santa Cruz Biotechnology was previously validated using D2 KO animals and the data have been published [27]

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