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In fact, vitamin B12 deficiency is a known contributor to neural tube defects

The symptoms of B12 deficiency can vary between people, regardless of sex

Additionally, researchers have observed interactions with the dopaminergic and serotonergic systems in neurological models, suggesting broad signaling pathway engagement

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Subcutaneous administration of vitamin B12 is sometimes employed, especially in patients with congenital cobalamin metabolism disorders who require high doses to maintain normal metabolic pathways