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Non-targeted lipidomic analysis revealed that levels of lysophosphatidylcholines (LysoPCs) and lysophosphatidylethanolamines (LysoPEs) were significantly increased in both GCH1-expressing and overexpressing cells following IKE treatment and contained PUFAs

Put on your gloves

That being said, minoxidil has more research behind it and is the only FDA-approved topical for androgenic alopecia

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Clonidine works through the brain and is often reserved for resistant hypertension or withdrawal-related symptoms, while propranolol acts on the heart and is commonly chosen when blood pressure control is needed alongside migraine prevention, anxiety symptoms, or heart conditions

When used together, they may cause dryness, peeling, or redness, especially for sensitive skin types or beginners