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If the issue was product quality from a grey-market source, the compound itself may work fine when sourced properly

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The hypovolemia triggers an increase in norepinephrine

Biomedicines 10:1544 Hall MD, Telma KA, Chang KE, Lee TD, Madigan JP, Lloyd JR, Goldlust IS, Hoeschele JD, Gottesman MM (2014) Say no to DMSO: dimethylsulfoxide inactivates cisplatin, carboplatin, and other platinum complexes