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Proton pump inhibitors (PPIs) are the most effective and commonly prescribed acid reflux drugs

As the insulin receptor is expressed in all cell types and insulin signaling mediates diverse cellular functions, the detailed insulin function of each tissue has been extensively studied using tissue-specific Insr knockout mice 3,5 , in which Insr expression is almost completely disrupted in a specific cell type

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In: Encyclopedia of Physical Science and Technology

and Brown, T

The studies demonstrate that in mice and rats microplastics may also cause biochemical and structural damage with noticeable dysfunctions of the intestine, liver, and excretory and reproductive systems