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JOP 6: 316-324, 2005

New evidence has indicated that mtDNA and mitochondrial extrusion via platelet activation through FcRIIA stimulation induces a circulatory autoantigenic load that ultimately leads to SLE pathogenesis (134, 135)

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Melanin is produced by melanocytes, which are the specialised pigment-producing cells found in the epidermis (outermost layer of the skin) 1,2