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10.1038/mp.2016.196 20 CardosoB
Enzyme-responsive cell-penetrating peptide conjugated mesoporous silica quantum dot nanocarriers for controlled release of nucleus-targeted drug molecules and real-time intracellular fluorescence imaging of tumor cells
Among these, magnesium and glutathione play particularly important roles
Glutathione + MOTS-c Frequently investigated in: Metabolic-regulation research Mitochondrial-signaling pathways Cellular-energy investigations Recovery-focused metabolic pathways Physiological-resilience research Research commonly explores the relationship between antioxidant-support pathways and mitochondrial-related signaling mechanisms
Glyburide, a sulfonylurea-containing diabetic drug known to inhibit ATP-sensitive K + - channels in the pancreas, also impedes NLRP3-activation and IL-1 production at micromolar concentrations upstream of inflammasome assembly and independent of effects on K + channels [99]
other studied peptides act through different mechanisms and routes
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