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In subunit 1, the N-terminal domain I helices are shown in dark blue, and -strands are shown in red, and the C-terminal domain II helices are shown in light blue

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Altogether, these results are consistent with CDK11 acting as a primary kinase for SF3B1 phosphorylation 8 , and suggest that P-SF3B1 is required for the efficient integration of SNIP1 and the RES complex to the spliceosome during its activation

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doi: 10.1007/s10571-024-01453-w 404 ZamanianJ