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By collaborating with in vitro diagnostic companies, we can develop, optimize, and validate the detection methods to ensure their reliability, sensitivity, and specificity

99 The gut microbiota Emerging studies have shown that the intestinal microbiota composition of obese people has changed compared with that of lean people, even though the reported changes are inconsistent or even contradictory

Other mechanisms include increased insulin resistance induced by high-dose glucocorticoids that increases intra-portal insulin, decreases IGFBP-1 that increases free IGF-I, and direct glucocorticoid effects in increasing hepatic IGF-I synthesis and decreasing hepatic insulin clearance (105)

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