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We investigated whether the observed depalmitoylation of ATG2A in starved cells was a consequence of APT1 activation or ZDHHC11 inactivation

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Categorical variables were analyzed by either Fisher's test or Pearson's chi-squared test

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Meanwhile, gut microbiota dysbiosis also had strong influence on OA development through the gut-joint axis: intestinal barrier disruption, increased endotoxemia throughout the body, and decreased SCFA all drove joint degeneration

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