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MOTS-c, being a peptide, is primarily studied through subcutaneous injection to ensure it reaches systemic circulation effectively

[39] The elderly are at increased risk because they tend to produce less stomach acid as they age, a condition known as achlorhydria, thereby increasing their probability of B 12 deficiency due to reduced absorption

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Dalton DA, Russell SA, Hanus F et al (1986) Enzymatic reactions of ascorbate and glutathione that prevent peroxide damage in soybean root nodules