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They may be used alone or synergistically with antifungals to alter gene expression related to adhesion, mycelial or biofilm formation, reduce extracellular polysaccharides, decrease surface hydrophobicity, or inhibit efflux pumps

SAM deficiency may lead to methyl deficiency, which is associated with the high incidence and mortality of DKD patients

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These findings have led researchers to examine BPC-157 in experimental systems studying receptor regulation, fibroblast proliferation pathways, and cross-talk between peptide signaling and anabolic regulatory mechanisms