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Since inflammatory cells secrete a large number of cytokines and chemokines, oxidative stress is triggered during inflammation, and overproduction of ROS is stimulated

J Affect Disord 40:2333

Results were published in Science and Geophysical Research Letters

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ROS-responsive nanoparticle delivery of ferroptosis inhibitor prodrug to facilitate mesenchymal stem cell-mediated spinal cord injury repair

These seemingly paradoxical effects may be one explanation for why patients with G6PD-d display increased susceptibility to infection indicative of an impaired immune response, while also displaying increased autoimmunity and inflammation indicative of an overactive immune system 13