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Due to excessive indoor living, our vitamin D levels are lower than previous generations

In the last 40 years, the ketogenic diet (KD) became a promising dietary intervention in some pathological conditions

Ethics declarations Ethics approval Ethics approval was not required, as the study was conducted using computer simulations

Chemokine receptor antagonists/IL8CXCR1/2 blockade: Since IL8 is a major upstream driver of neutrophil chemotaxis and NETosis, pharmacologic antagonism of IL8 or its receptor axis (CXCR1/CXCR2) is under exploration in oncology and inflammatory disease [56]

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Glutathione or NAC is taken daily, ideally split into morning and evening doses to maintain steady antioxidant coverage throughout the day