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Campagna, R., et al

Research has suggested that AHK-Cu may participate in cellular signaling and regulation processes, with particular interest in vascular endothelial cells and fibroblasts

However, absorption decreases significantly as doses increase, and individuals with compromised gut health may absorb only 1-2%

The authors reported that AOD-9604 stimulated lipolysis in isolated adipocytes and that chronic daily treatment in obese Zucker rats produced reductions in body weight gain of more than 50% relative to untreated controls over the treatment period, without effects on insulin sensitivity or IGF-1 levels [3]

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[21] When treated with cyanocobalamin, patients with Leber's disease may develop serious optic atrophy, possibly leading to blindness, based on few case reports