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While lipid-calcium-phosphate (LCP) NPs showed early promise in antigen delivery for primary melanoma, their efficacy in late-stage disease was constrained by TGF--mediated immune suppression (93)

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After supplementation with 10% glycerol, aliquots of purified protein were flash-frozen in liquid nitrogen and stored at 80 C until further use

Importantly, the SLE Disease Activity Index 2K (SLEDAI-2K) score in the synbiotic group improved dramatically from 14 (159)

Phase 3 trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter