However, it never received FDA approval because the results, while positive, weren't dramatic enough to meet regulatory thresholds for an obesity drug
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where it appears in clinical or off-label use, it does so through compounding channels that federal regulators have since restricted (see legal status below)
This inevitably results in low IGF-I and high GH that may stray into the acromegaly range (132, 133) and this catabolic state is comparable to prolonged fasting and malnutrition states ( Figure 1E )
Journal of Clinical Medicine, 12, 7120
If appropriate, your provider creates a personalized peptide therapy plan