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The administration of urolithin A mitigates barrier dysfunction and colitis development in the mouse model of 2,4,6-trinitrobenzene sulfonic acid-induced colitis

When the body is in a state of hypoxia, infection, intense exercise, etc, and the cells demand for ATP increases, pyruvate and NADH tends to be directly catalyzed by lactate dehydrogenase (LDH) to produce lactate, rather than entering the mitochondria to participate in the tricarboxylic acid cycle (TCA)

Any soreness usually fades within a few hours

doi: 10.1074/jbc.M202919200

In normoxic tumor zones, cancer cells can utilize oxidative metabolism more efficiently by scavenging CAF-derived metabolites, thereby conserving their own glucose and glutamine pools (148)

222 In addition to its role in oncology, BRD4 regulates autophagy