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Combination therapies Interleukin 21, a cytokine primarily synthesized by T helper cells, is linked to autoimmune disorders, with heightened IL-21 levels detected in both peripheral blood and tissues of individuals with T1D [77]

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518,519,520 Besides, through maintaining the rate of NAD + production and normalizing the NADH/NAD + balance, both pentylenetetrazole (PTZ) and niacin (NA) exhibit neuroprotective properties

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