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In this model we exposed BALB/c mice to Alternaria alternata and treated them with melatonin both at 17:00, since this is a time point that has been found to result in the most severe induction of features of allergic airway pathology (42)

Researchers planning new work should review the most current literature before designing protocols, with attention to the gap between preclinical breadth and clinical-trial depth

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[14]Gasperl A, Zellnig G, et al