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[DOI] [PMC free article] [PubMed] [Google Scholar] 39.Yajnik CS, Deshpande SS, Jackson AA, Refsum H, Rao S, Fisher DJ, Bhat DS, Naik SS, Coyaji KJ, Joglekar CV, et al

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Some compounded Lipo-B products may specify storage at room temperature or refrigerated

[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations

Limited data indicate vitamin B12 deficiency may contribute to menstrual irregularities (but more study is needed)